National Awards “Science and Research”
NEW! RMJ has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.
Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.
The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.
TUMORAL MARKERS IN OVARIAN CANCER – A LITERATURE REVIEW
Nicolae BACALBASA, Alexandra Gireada and Irina BALESCU
Ovarian cancer is one of the most lethal malignancies due to an aggressive biological behavior of a tumor usually diagnosed in an advanced stage of the disease. Due to the fact that important differences in terms of survival have been observed between cases diagnosed in early stages when compared to those in FIGO stages III-IV, attention was focused on establishing which is the most appropriate laboratory diagnostic test which could help the clinician to diagnose and treat the disease in a less advanced stage. This is a literature review of the most frequently used tumor markers and scores used in ovarian cancer diagnostic and follow up.
Keywords: ovarian cancer, CA 125, HE 4, ROMA score, OVA1