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ISSN-L 1220-5478
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HIGHLIGHTS
Premiul Societatii pentru autori
Incepand cu 2016, Asociatia Medicala Romana ofera Premiul Societatii - pentru autorii celor mai bune articole stiintifice publicate [...]
Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]
SERONEGATIVE ANTIPHOSPHOLIPID SYNDROME
Manole Cojocaru, Inimioara Mihaela Cojocaru and Bogdan Chicos
ABSTRACT
Seronegative antiphospholipid syndrome (seronegative APS) has remained an enigma and the concept is controversial. A small group of APS patients remain persistently negative for routine assays of antiphospholipid (aPL) antibodies. The clinical features are well defined, and include the tendency to both arterial and venous thrombosis, to recurrent miscarriages, and to occasional thrombocytopenia. Patients with clinical manifestations highly suggestive of APS but persistently negative conventional aPLs are classified as having seronegative APS.
Keywords: seronegative antiphospholipid syndrome, negative antiphospholipid antibodies, clinical features